Linear empirical Bayes estimation of means and variances.
نویسندگان
چکیده
منابع مشابه
Variance adaptive shrinkage (vash): flexible empirical Bayes estimation of variances
MOTIVATION Genomic studies often involve estimation of variances of thousands of genes (or other genomic units) from just a few measurements on each. For example, variance estimation is an important step in gene expression analyses aimed at identifying differentially expressed genes. A common approach to this problem is to use an Empirical Bayes (EB) method that assumes the variances among gene...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1985
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.82.6.1571